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Dasiel O. Borroto-Escuela


Dasiel O. Borroto-Escuela

Karolinska Institutet, Sweden

Biography

Since 2008, PhD from Polytechnic University of Catalonia, Spain. Since 2009, he is a contracted Postdoctoral Researcher at the Department of Neuroscience, Karolinska Institutet, who has primarily focused on understanding whether alterations in specific heteroreceptor complexes and their receptor-receptor interactions are associated with and/or play a role in pathogenetic mechanisms contributing to brain disease development, inter alia Parkinson's disease, schizophrenia, addiction and depression. He has received a significant number of awards, among them the UPC Excellence Thesis Award, the FEBS-YSF 2013, the ECNP 2014 Fellow Award and published over 70 papers in neuroscience in the last five years. His major achievements involve pioneering work on the understanding the molecular integration of signals in the brain via receptor-receptor interaction in heteroreceptor complexes and its functional effects. Also, in the implementation of new innovative tools and screening technologies to identify GPCR oligomers.

Abstract

Abstract : On the role of A1-D1 heteroreceptor complexes in the direct pathway in models of Parkinson's disease