Parkinson’s Disease & Movement Disorders

Biography

Dasiel O Borroto-Escuela has completed his PhD from Polytechnic University of Catalonia, Spain. Since 2009, he has been a Contracted Postdoctoral Researcher at the Department of Neuroscience, Karolinska Institutet. His primary focus is on understanding whether alterations in specific heteroreceptor complexes and if their receptor-receptor interactions are associated with and/or play a role in pathogenetic mechanisms contributing to brain disease development, inter alia Parkinson’s disease, schizophrenia, addiction and depression. He has received a significant number of awards, among which are the UPC Excellence Thesis Award, the FEBSYSF 2013, the ECNP 2014 Fellow Award. He has published over 70 papers in neuroscience in the last five years. His major achievements involve pioneering work on understanding the molecular integration of signals in the brain via receptor-receptor interaction in heteroreceptor complexes and its functional effects also, in the implementation of new innovative tools and screening technologies to identify GPCR oligomers.

Abstract

Abstract : On the role of A1-D1 heteroreceptor complexes in the direct pathway in models of Parkinson’s disease